Case Studies & Example Workflows

Representative, real-world inspired analytics workflows showing how teams use Sigma BioAnalytics to design studies, clean data, and generate regulatory-ready insights — without spreadsheets or custom code.

How Teams Use Sigma in Practice

The examples below illustrate common analytical workflows supported by the Sigma platform. All case studies are anonymised and representative — designed to demonstrate methodology, transparency, and regulatory alignment rather than disclose client data.

What Teams Are Achieving With Sigma

A selection of real-world inspired workflows illustrating how the platform delivers value across study design, PK/PD modeling, RWE, and automated reporting.

Validated Sample Size & Power Exploration

A biotech team explored multiple design scenarios using Sigma’s built-in sample size engine — generating power curves, sensitivity analyses, and protocol-ready justification in minutes.

  • Binary & continuous endpoints
  • 80% / 90% power sensitivity
  • Automated PDF & Word reports
Sample Size & Trial Design
Clinical Trial Benchmarking & RWE Insights

A clinical strategy group benchmarked protocol assumptions against historical trials — comparing enrolment, duration, and success rates using Sigma’s Clinical Trial Intelligence workflows.

  • Trial similarity matching
  • Survival & outcome benchmarking
  • HTA-ready summaries
Clinical Trial Intelligence
Automated Data Cleaning & QC

A CRO automated anomaly detection, missing data checks, and data validation workflows — producing a clean analysis-ready dataset with full audit trails.

  • Missingness profiling
  • Outlier & anomaly detection
  • Transformation & Visualisation
  • Merging & appending several datasets
  • Report + clean dataset export
Data Quality

Apply These Workflows to Your Study

Use Sigma independently through a monthly subscription, or combine the platform with expert statistical support.